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HIV/AIDS: The search for a vaccine

Originally aired as part of BBC World's "Kill or Cure?" series, this 4-minute documentary features AIDS specialists, researchers ...

New Study May Aid Search for AIDS Vaccine

New Paths for AIDS Vaccine

Vaccines that target viruses work by training the immune system to recognize and kill invading viruses. They do this by exposing the body to a harmless form of the targeted virus.

The reason it has been so hard to develop a vaccine against HIV is that the virus mutates far more often than most other disease-causing pathogens.

“Unlike other viruses, like measles or polio, you can’t just make a weakened form because HIV is crafty enough that if you weaken it the virus figures out a way to return to its virulent form,” IAVI Chief Science Officer Wayne Koff, PhD, tells WebMD.

Although earlier research has identified the outer protein coating of the HIV virus as a major target of antibodies that inhibit infection, Koff says investigators had not previously identified the specific vulnerable sites on the protein to target with a vaccine.

Within a few years of infection most people who are HIV positive do not produce virus-targeting antibodies, but a minority of patients do.

Aids Vaccine - Bookshelf


AIDS vaccine development, challenges and opportunities
151 pages
AIDS vaccine development, challenges and opportunities

This book reviews the scientific challenges that have impeded the search for an effective AIDS vaccine and discusses current novel research that is accelerating ...

AIDS vaccine research
342 pages
AIDS vaccine research

With contributions by universally recognized authorities in the field, AIDS Vaccine Research discusses major obstacles in the identification of a preventive ...

The search for an AIDS vaccine, ethical issues in the development and testing of a preventive HIV vaccine
193 pages
The search for an AIDS vaccine, ethical issues in the development and testing of a preventive HIV vaccine

"The book is a balanced and comprehensive treatment of an important social issue.

Jet
68 pages
Jet

AIDS Vaccine May Prevent Disease In Blacks the week's best photos - • . *LX m HEALTH AIDS is the leading cause of death among Black women ages 25-34 and ...

Unraveling aids, the independent science and promising alternative therapies
231 pages
Unraveling aids, the independent science and promising alternative therapies

NO EFFECTIVE VACCINE IN SIGHT AFTER TWENTY YEARS The International AIDS Vaccine Initiative (IAVI) describes itself as “a global not-for-profit organization ...

Digg Headlines

(1 diggs) Aids Vaccine Federal andrewbreath Aids Vaccine Federal. The quality articles are selected related closely with topic Aids Vaccine Federal
(1 diggs) Antibodies and AIDS: Vaccine Breakthrough? byteforbyte Newly Discovered Antibodies Could be the Key. Researchers may be closer to a finding a vaccine than ever before because they say they have found human antibodies that can "neutralize" 90 percent of the HIV mutations that cause AIDS.
(1 diggs) AIDS Vaccine animalherders AIDS vaccine promising; experts urge caution
(1 diggs) International Aids Vaccine Initiative alafiyakapadia International Aids Vaccine Initiative. The quality articles are selected related closely with topic International Aids Vaccine Initiative
(1 diggs) Promising target for AIDS vaccine longbenavery A section of the AIDS virus's protein envelope once considered an improbable target for a vaccine now appears to be one of the most promising, new research indicates. The section, a twisting strand of protein known as the V3 loop, is an attractive vaccine target because immune system antibodies aimed at the loop may offer protection against multiple genetic subtypes of HIV-1.

New Study May Aid Search for AIDS Vaccine

Aug. 17, 2011 -- In the spring of 1997, then-president Bill Clinton called for an effective AIDS vaccine within a decade. Fourteen years and billions of research dollars later, a vaccine to prevent HIV infection remains an elusive goal.

International efforts to develop a useful HIV vaccine have proven disappointing, with failed clinical trials and dashed hopes. But a new study may represent an important break in the search.

Researchers with the Scripps Howard Research Institute and the International AIDS Vaccine Initiative (IAVI) have identified 17 new antibodies with broad activity against HIV.

Some of the antibodies are 10 times more potent than any that had previously been identified, and the hope is that they will turn out to be new targets for potential HIV vaccines.

The research appears today in the online issue of the journal Nature.

New Paths for AIDS Vaccine

Vaccines that target viruses work by training the immune system to recognize and kill invading viruses. They do this by exposing the body to a harmless form of the targeted virus.

...

Read more...

Aids Vaccine - News


HIV Vaccine Development Helped By New Antibodies
HIV Vaccine Development Helped By New Antibodies An HIV vaccine may be closer since researchers have identified 17 new antibodies with broad activity against HIV. The scientists, who are from the Scripps Howard Research Institute and the International AIDS Vaccine Initiative (IAVI),

New Study May Aid Search for AIDS Vaccine
New Study May Aid Search for AIDS Vaccine 17, 2011 -- In the spring of 1997, then-president Bill Clinton called for an effective AIDS vaccine within a decade. Fourteen years and billions of research dollars later, a vaccine to prevent HIV infection remains an elusive goal.

GeoVax Receives Latest Tranche of $19.6M NIAID Funding for HIV Vaccine
GeoVax Labs has received the latest $3.6 million tranche of a (to date) $19.6 million Integrated Preclinical/Clinical AIDS Vaccine Development (IPCAVD) grant awarded by the National Institute of Allergy and Infectious Diseases, to support the firm's

US Scientists Expand Scope of HIV Vaccine Study
“The trial is being expanded both in terms of the number of participants, as well as what the trial is looking to answer,” said Mitchell Warren, head of AVAC, the AIDS Vaccine Advocacy Coalition, who's following the study's developments.

GeoVax Labs, Inc. Announces Second Quarter Financial Results
Net losses were partially offset by revenues related to the Company's grant from the NIH in support of the its HIV/AIDS vaccine development activities; such revenues were $1753033 and $2646035 for the three month and six month periods of 2011,

AIDS Directory

International AIDS Vaccine Initiative
Scientific nonprofit organization working to speed the development and distribution of preventive AIDS vaccines.

HIV and AIDS Vaccine
Why do we need an HIV and AIDS vaccine? What vaccine trials are underway? Who is supporting research and development for a vaccine against HIV and AIDS? ...

HIV vaccine - Wikipedia, the free encyclopedia
Currently, there is no effective vaccine against HIV, the virus that causes AIDS. ... The Thai trial was the largest AIDS vaccine trial to date when it started.[22] ...

AIDS Vaccine Success Is 'Modest'
A combination of two HIV vaccines cuts HIV infections by 31% -- the first such success in humans and evidence that a more effective AIDS vaccine is possible.

AIDS Vaccines: The Ethical and Social Issues - The Body
After years of frustration, there is renewed optimism in the vaccine field. Promising research findings combined with new infusions of interest (and ...